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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TERT
All Species:
39.39
Human Site:
S457
Identified Species:
72.22
UniProt:
O14746
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14746
NP_937983.2
1132
126997
S457
Q
L
L
R
Q
H
S
S
P
W
Q
V
Y
G
F
Chimpanzee
Pan troglodytes
XP_001141663
1135
126922
S457
Q
L
L
R
Q
H
S
S
P
W
Q
V
Y
G
F
Rhesus Macaque
Macaca mulatta
XP_001096904
1132
126842
S457
Q
L
L
R
Q
H
S
S
P
W
Q
V
Y
G
F
Dog
Lupus familis
XP_851664
1092
121456
S446
Q
L
L
R
Q
H
S
S
P
W
Q
V
Y
A
F
Cat
Felis silvestris
Mouse
Mus musculus
O70372
1122
127960
S447
D
L
L
R
L
H
S
S
P
W
Q
V
Y
G
F
Rat
Rattus norvegicus
Q673L6
1125
126915
S447
S
L
L
R
L
H
S
S
P
W
Q
V
Y
G
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026178
1346
155264
S666
E
L
L
R
Q
H
S
S
H
W
Q
V
Y
G
F
Frog
Xenopus laevis
NP_001079102
1191
137998
S511
S
L
L
K
Q
H
S
S
I
W
Q
V
Y
M
F
Zebra Danio
Brachydanio rerio
NP_001077335
1098
125968
S443
S
L
L
K
S
H
S
S
P
Y
R
V
Y
L
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781093
1312
150053
T636
R
L
P
N
D
A
A
T
L
I
K
M
K
T
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001105870
1188
135970
T515
V
Q
L
E
A
Y
S
T
H
Q
Q
V
V
S
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_197187
1123
130561
T449
E
E
R
K
L
Y
C
T
N
D
Q
V
V
S
F
Baker's Yeast
Sacchar. cerevisiae
Q06163
884
102645
S272
E
G
T
V
L
D
L
S
H
L
S
R
Q
S
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
95.8
70.3
N.A.
63.3
63.3
N.A.
N.A.
45.2
42.9
32.8
N.A.
N.A.
N.A.
N.A.
27
Protein Similarity:
100
97.9
97.4
77.5
N.A.
74
73.5
N.A.
N.A.
58.2
60.1
50.8
N.A.
N.A.
N.A.
N.A.
42
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
86.6
73.3
60
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
93.3
80
80
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
24.7
N.A.
24.8
20.7
N.A.
Protein Similarity:
N.A.
40.4
N.A.
42.6
36.9
N.A.
P-Site Identity:
N.A.
33.3
N.A.
20
6.6
N.A.
P-Site Similarity:
N.A.
46.6
N.A.
46.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
8
0
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
8
8
0
0
0
8
0
0
0
0
8
% D
% Glu:
24
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
85
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
0
0
0
47
0
% G
% His:
0
0
0
0
0
70
0
0
24
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% I
% Lys:
0
0
0
24
0
0
0
0
0
0
8
0
8
0
0
% K
% Leu:
0
77
77
0
31
0
8
0
8
8
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% M
% Asn:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
54
0
0
0
0
0
8
% P
% Gln:
31
8
0
0
47
0
0
0
0
8
77
0
8
0
0
% Q
% Arg:
8
0
8
54
0
0
0
0
0
0
8
8
0
0
0
% R
% Ser:
24
0
0
0
8
0
77
77
0
0
8
0
0
24
0
% S
% Thr:
0
0
8
0
0
0
0
24
0
0
0
0
0
8
0
% T
% Val:
8
0
0
8
0
0
0
0
0
0
0
85
16
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
62
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
16
0
0
0
8
0
0
70
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _